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The best way to find the best b12 and folate supplement is by taking a look at what other people are buying and which brands they prefer. You can also take a look at the reviews and ratings of the product.

The following table provides concise information about how to pick a product from online:

  • Consider what you want
  • Find out what other people are buying
  • Look at reviews and ratings
  • Compare prices
  • Beware of scams

Top 10 best b12 and folate supplement Features Overview

Here are the of top 10 b12 and folate supplement we picked and recommend.

1. Life Extension BioActive Folate & Vitamin B12 – Promotes Heart, Brain & GI Tract Health – Gluten-Free, Non-GMO, Vegetarian – 90 Vegetarian Ca



  • POWERFUL “B” COMBINATION – We’ve combined the active forms of folate (as 5-MTHF) and vitamin B12 (as methylcobalamin). Together, these nutrients (both members of the vitamin Bfamily) promote heart, brain and digestive health. 5-MTHF is the only form of folate used directly by the body, and it’s up to seven times more bioavailable than folic acid.
  • WHAT DOES FOLATE DO? – Folate is a form of vitamin B. It is found in abundance in leafy greens vegetables. Folate helps promote healthy DNA function, maintains already normal homocysteine levels, supports heart health, promotes healthy skin, a healthy digestive tract, and even a healthy immune response.
  • A LITTLE EXTRA VITAMIN B12 – Vitamin B12 supports brain and heart health by helping to maintain healthy homocysteine levels. And when combined with folate, B12 helps with red blood cell production, too. We use methylcobalamin, the bioactive form of this vitamin.
  • INGREDIENTS MATTER – Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
  • LIVE YOUR HEALTHIEST LIFE – For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.





2. Jarrow Formulas Methyl B-12 & Methyl Folate – 100 Chewable Tablets, Lemon – Bioactive Vitamin B12 & B9 – Supports Energy Production, Brain Function



  • Bioactive B Vitamins: Methyl B-12 and Methyl Folate provides methylcobalamin (methyl B-12) and methyl folate, which are the biologically active forms of vitamin B12 and B9, plus pyridoxal-5-phosphate (P5P), the coenzyme form of vitamin B6
  • Full-Body Benefits: This Jarrow Formulas supplement combines the active forms of these vitamins to support energy production, brain function, DNA and neurotransmitter synthesis, and amino acid metabolism
  • Homocysteine Metabolism: Methyl B-12 and methyl folate facilitate the metabolism of homocysteine into methionine, while P5P facilitates the metabolism to cysteine
  • Convenient Chewable Tablet: Each lemon-flavored chewable tablet delivers 1.5 mg of vitamin B6, 680 mcg of folate, and 1000 mcg of vitamin B12; Our formula contains no wheat, gluten, soybeans, dairy, egg, fish, shellfish, or peanuts and tree nuts
  • Superior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency





3. Pure Encapsulations B12 Folate | Energy Supplement to Support Emotional Wellness, Nerves, and Cognitive Health* | 60 Capsules



  • Energy Metabolism: Vitamins B12 and Folate helps convert carbohydrates into energy and break down fats and proteins in the body.*
  • Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the functionality of the nervous system as well as your hair, skin, and liver.*
  • Cognitive Support: Folate is essential for healthy fetal neural development while B12 is an important nutrient for memory and cognitive function.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn’t just our process or what goes into our supplements — what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.





4. Jarrow Formulas Methyl B-12 & Methyl Folate – 60 Chewable Tablets, Cherry – Bioactive Vitamin B12 & B9 – Supports Energy Production, Brain Function



  • Bioactive B Vitamins: Methyl B-12 and Methyl Folate provides methylcobalamin (methyl B-12) and methyl folate, which are the biologically active forms of vitamin B12 and B9, plus pyridoxal-5-phosphate (P5P), the coenzyme form of vitamin B6
  • Full-Body Benefits: This Jarrow Formulas supplement combines the active forms of these vitamins to support energy production, brain function, DNA and neurotransmitter synthesis, and amino acid metabolism
  • Homocysteine Metabolism: Methyl B-12 and methyl folate facilitate the metabolism of homocysteine into methionine, while P5P facilitates the metabolism to cysteine
  • Convenient Chewable Tablet: Each cherry-flavored chewable tablet delivers 2.5 mg of vitamin B6, 1360 mcg of folate, and 5000 mcg of vitamin B12; Our formula contains no wheat, gluten, soybeans, dairy, egg, fish, shellfish, or peanuts and tree nuts
  • Superior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency





5. NATURELO B Complex – Whole Food Complex with Vitamin B6, Folate, B12, Biotin – Supplement for Energy and Stress – High Potency – Vegan – Vegetarian



  • Complete B Complex: All 8 B vitamins, including Thiamine (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Biotin (B7), Folate (B9), B6 and B12, with important co-nutrients like Choline, Inositol, and PABA, plus CoQ10.
  • Potent & Bioactive: High potency B complex multivitamin with the active, MTHFR-friendly forms of Folate (5-Methyl Folate), B6 (P-5-P) and B12 (Methycobalamin), which can be used directly by the body.
  • B Vitamin Benefits: B Complex Vitamins support Energy Production and Metabolism, Healthy Brain and Nervous System Function, Heart Health, and a Healthy Pregnancy.*
  • Whole Food Complex: Our plant-based supplement includes a blend of organic fruits and vegetables for an extra boost of whole food nutrition with natural vitamins, minerals and antioxidants.
  • Clean Label: Non GMO. Gluten Free. Vegan-Friendly. Does NOT Contain Soy, Dairy, Yeast, Eggs, Nuts, Caffeine, Preservatives, Coloring, or Flavoring.





6. Super B-Complex – Methylated Sustained Release B Complex & Vitamin C, Folate & Methylcobalamin, Vegan, 60 Small Tablets



  • HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Nicotinamide (flush free Niacin – B3), Calcium D-pantothenate (B5) & D-Biotin (B7)
  • METHYLATED VITAMIN FORMS that the body utilises immediately: bioavailable folate as Quatrefolic, Pyridoxal-5-Phosphate (Vit B6), methylcobalamin (Vit B12) – no poorly absorbed cyanocobalamin
  • SUSTAINED RELEASE provides all-day nutrient coverage and twice daily dosing optimises B12 levels
  • INTENSIVE HEALTH SUPPORT for energy metabolism, the immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function, psychological function
  • GMP MANUFACTURED IN THE USA. Vegetarian & Vegan. MTHFR friendly (no synthetic folic acid). Small tablets (9mm)





7. Vital Nutrients – Vitamin B12 / Methyl Folate – Supports Healthy Brain Cell Function – 100 Vegetarian Capsules per Bottle



  • GI Health: Vitamin B12 & Folate work together to support the health of the gastrointestinal tract
  • Nerve Support Formula: Methylated forms of B12 & folate are considered to be the most bioavailable
  • Prenatal Vitamins: Folate as L-5-MTHF 800mcg may reduce the risk of neural tube birth defects
  • Quality, Purity & Potency: No coatings or binders, gluten-free, dairy-free, soy-free & sugar-free
  • Vital Nutrients: Committed to making high-quality supplements that support health & vitality





8. NOW Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets



  • CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.*
  • METABOLICALLY ACTIVE FOLATE*/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968





9. L Methyl Folate 15mg Plus Methyl B12 Cofactor – Professional Strength, Active 5-MTHF Form – Supports Mood, Homocysteine Methylation, Cognition (60



  • PROFESSIONAL STRENGTH: Provides clinically validated dosage of 15mg L Methyl folate in the 5-MTHF calcium salt form. This is the most active form of Folate.
  • ESSENTIAL METHYL B12 COFACTOR: Methylcobalamin B12 and Methylfolate have co-dependent relationships. Both are crucial in the body’s methylation processes. Methylfolate cannot complete the methylation process and breakdown of homocysteine without Methyl B12.
  • ACTIVE FORM OF FOLATE: Methylfolate is the most metabolically active and bloodstream-ready form of Folate or Folic Acid (vitamin B9). It is immediately absorbed into the bloodstream because it does not require processing or breakdown by the body. This is crucial for those with methylation issues that cannot properly process folic acid.
  • BRAIN, MOOD & ENERGY SUPPORT: Essential to neurotransmitters production involved in concentration, sleep, energy, hormones & mood.*
  • CARDIOVASCULAR, NITRIC OXIDE & NERVE SUPPORT: Supports heart health and nerve function by supporting healthy homocysteine levels and nitric oxide production.





10. Pure Encapsulations – PureMelt B12 Folate – Sugar-Free Dissolvable Lozenge with 1,000 mcg Vitamin B12 and Active Folate (as Metafolin L-5-MTHF) –



  • Activated B Vitamins: PureMelt B12 Folate contains a combination of activated vitamin B12, as methylcobalamin, and Metafolin 5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate.
  • Great Taste: Great tasting, fruit flavored lozenge uniquely designed to dissolve in the mouth without requiring water.
  • Cellular Health: Activated B vitamins provide methyl groups to support healthy methylation, a key regulator of genetic expression and cellular function.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn’t just our process or what goes into our supplements — what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.





Conclusion

There is a myriad of online stores out there, and it is impossible for one to compare the different b12 and folate supplement as well as their prices since not all websites offer them. Online shoppers often turn to reviews and customer feedback for help, but even these are unreliable sources. Sometimes people post negative reviews just to be spiteful or angry.

The lack of insightful information online forces shoppers to rely on the information they find elsewhere, but this can lead to misinformation and incorrect purchase decisions.

Consumers can save themselves from these potential risks by turning to an AI-powered shopping assistant that provides tailored product suggestions based on their preferences.

But Amazon made the whole process easy and effortless.

Why You Trust Amazon?

As they grow increasingly popular, there are some challenges that people face when they try to purchase something on the internet. There are many reasons why people might not trust Amazon as much anymore:

  • They worry about their personal information being stolen;
  • They question the reliability of the website;
  • Its security features and whether or not their credit card details will be safe
  • The quality of products sold by third parties might not be as good
  • There’s no instant gratification with online purchases;

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